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mapk_pathway_drugs_ocular_toxicity [2026/07/01 22:24] – [Pan-RAF Inhibitors] Scott Larsonmapk_pathway_drugs_ocular_toxicity [2026/07/01 22:29] (current) – Scott Larson
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 ===== The MAPK Cascade ===== ===== The MAPK Cascade =====
 The MAPK/RAS-RAF-MEK-ERK cascade is a highly conserved, three-tiered signaling pathway that transmits extracellular signals from the cell surface to the nucleus, regulating cell proliferation, differentiation, survival, and migration. The MAPK/RAS-RAF-MEK-ERK cascade is a highly conserved, three-tiered signaling pathway that transmits extracellular signals from the cell surface to the nucleus, regulating cell proliferation, differentiation, survival, and migration.
 +[[https://onlinelibrary.wiley.com/cms/asset/62ef33b9-04f0-4739-b255-aaa5a35df3c1/cns14807-fig-0001-m.jpg|Diagram of Pathway]]
  
 ==== Step-by-Step Signal Transduction ==== ==== Step-by-Step Signal Transduction ====