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sjogren_syndrome [2023/03/07 14:44] – Scott Larsonsjogren_syndrome [2026/07/28 12:24] (current) – [Diagnostic Criteria 2016] Scott Larson
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 ===== Diagnostic Criteria 2016 ===== ===== Diagnostic Criteria 2016 =====
 +<WRAP round box 80%>
 |Item|Weight/Score| |Item|Weight/Score|
 |Anti-SSA / Ro antibody positivity|3| |Anti-SSA / Ro antibody positivity|3|
-|Focal lymphocytic sialadenitis with a focus score of ≥ 1 foci / 4 mm²|3|+|Focal lymphocytic sialadenitis* with a focus score of ≥ 1 foci / 4 mm²|3|
 |Abnormal ocular staining score of ≥ 5 (or van Bijsterveld score of ≥ 4) |1| |Abnormal ocular staining score of ≥ 5 (or van Bijsterveld score of ≥ 4) |1|
 |Shirmer's test (no local anesthetic) result of ≤ 5mm / 5 minutes|1| |Shirmer's test (no local anesthetic) result of ≤ 5mm / 5 minutes|1|
 |Unstimulated salivary flow rate of ≤ 0.1 ml/minute|1|  |Unstimulated salivary flow rate of ≤ 0.1 ml/minute|1| 
 +*A histological feature defined by tightly-aggregated mononuclear cells adjacent to striated ducts
 +
 Source: {{ ::shiboski_-_2016_american_college_of_rheumatology_european_league_against_rheumatism.pdf |Shiboski et. al. 2016 American College of Rheumatology Classification Criteria for Primary Sjögren's Syndrome}} Source: {{ ::shiboski_-_2016_american_college_of_rheumatology_european_league_against_rheumatism.pdf |Shiboski et. al. 2016 American College of Rheumatology Classification Criteria for Primary Sjögren's Syndrome}}
 +</WRAP>
 {{tag>syndrome}} {{tag>syndrome}}